In Chiapas, about a quarter of the population is of indigenous origin. Most live according to their century-old customs, which include a closeness to nature and self-subsistence via farming (mainly corn and beans). Unfortunately, the socioeconomic status of this population is very poor.

Eighty-nine percent of the patient population served by Hospital San Carlos is indigenous; Tzeltal is the primary indigenous community, followed by Tojolabal, and lastly by Cho'ol and Tsotzil. 

San Carlos Hospital provides health care in a humanistic fashion, without discrimination, and with respect for and understanding of the diverse cultures in the region. The hospital struggles to provide quality service at a cost affordable to patients and often accepts barter as a form of payment. 

The open architecture of the hospital, almost contiguous with its surrounding gardens, creates a familiar environment for patients and workers who are used to living surrounded by nature.
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